于春梅 教授
苏州大学分析化学专业博士毕业,教授。现任南通大学公共卫生学院卫生检验与检疫学系主任,硕士生导师。先后在美国加州大学圣地亚哥分校、美国南卡罗莱纳大学访学。近年来主持完成国家自然科学基金2项,江苏省自然科学基金1项,江苏省高校自然科学基金1项,南通市应用研究项目3项。以第一和通讯作者发表 SCI 收录论文26篇,其中一区论文10篇。获江苏省科技进步二等奖1项(排名第二),南通市优秀自然科学论文一等奖和三等奖各1项。先后入选江苏省“333工程”高层次人才、江苏省“青蓝工程”中青年学术带头人、江苏省“六大人才高峰”高层次人才培养对象。曾获 “南通大学优秀教育工作者”、“南通大学巾帼先进个人”、“南通大学本科生毕业论文优秀指导教师”、 “南通大学优秀共产党员”等荣誉称号。
招生方向:
1. 生物纳米电化学:
将细胞生物学、分子生物学、材料科学、信息学、电子学及化学特别是电分析化学等学科有机地结合起来,利用表面自组装技术和纳米技术,将生物大分子、细胞等组装在纳米粒子修饰的电极表面,进行“生物与纳米电化学”研究,实现生命过程中某些功能分子特别是细胞转导分子的实时监测。
2.卫生检验:
将新型纳米材料应用于卫生分析领域,结合纳米技术与电分析技术,研究与人体健康管环境、食品及生物材料中环境雌激素、食品添加剂、残留农药等有害物质的高灵敏测定,构建用于实际样品检测的电化学传感器。
代表论文:
1. Jing Li#, Xin Huang#, Weishan Shi, Mengyuan Jiang, Liang Tian, Mengjie Su, Jie Wu, Quan Liu, Chunmei Yu*, Haiying Gu*. Pt nanoparticle decorated carbon nanotubes nanocomposite based sensing platform for the monitoring of cell-secreted dopamine. Sensors and Actuators B: Chemical, 2021, 330.
2. Linyi Xu, Jing Li, Weishan Shi, Ning Bao, Chunmei Yu*. Immobilization of hemoglobin on MnCO3 sphere-loaded Au nanoparticles as highly efficient sensing platform towards hydrogen peroxide. Nanotechnology, 2021, 32 (2) 025503.
3. Weishan Shi, Jing Li, Jie Wu, Qianying Wei, Cuili Chen, Ning Bao, Chunmei Yu*, Haiying Gu*. An electrochemical biosensor based on multi-wall carbon nanotube–modified screen-printed electrode immobilized by uricase for the detection of salivary uric acid. Analytical and Bioanalytical Chemistry, 2020, 412:7275–7283.
4. Xin Huang, Weishan Shi, Jing Li, Ning Bao, Chunmei Yu*, Haiying Gu*. Determination of salivary uric acid by using poly(3,4-ethylenedioxythipohene) and graphene oxide in a disposable paper-based analytical device. Analytica Chimica Acta, 2020, 1103: 75–83.
5. Xin Huang, Weishan Shi, Ning Bao, Chunmei Yu*, Haiying Gu*. Electrochemically reduced graphene oxide and gold nanoparticles on an indium tin oxide electrode for voltammetric sensing of dopamine. Microchimica Acta, 2019, 186: 310–317.
6. Chunmei Yu*, Xin Huang, Dongping Qian, Fengfeng Han, Linyi Xu, Yuejing Tang, Ning Bao, Haiying Gu*. Fabrication and evaluation of hemoglobin-based polydopamine microcapsules as oxygen carriers. Chemical Communication, 2018, 54, 4136–4139.
7. Chunmei Yu, Dongping Qian, Xin Huang, Fengfeng Han, Ning Bao, Haiying Gu. Construction of biconcave hemoglobin-based microcapsules and electrochemical evaluation for its ability of oxygen carry. Sensors and Actuators B, 2018, 256: 217–225.
8. Dongping Qian, Fengfeng Han, Weibo Li, Ning Bao, Chunmei Yu*, Haiying Gu*. Sensitive determination of sialic acid expression on living cells by using an ITO electrode modified with graphene, gold nanoparticles and thionine for triple signal amplification. Microchimica Acta, 2017, 184:3841–3850.
9. Dongping Qian, Weibo Li, Fangting Chen, Ying Huang, Ning Bao, Haiying Gu*, Chunmei Yu*. Voltammetric sensor for trichloroacetic acid using a glassy carbon electrode modified with Au@Ag nanorods and hemoglobin. Microchimica Acta, 2017, 184: 1977–1985.
10. Chunmei Yu, Qiuhong Wang, Dongping Qian, Weibo Li, Ying Huang, Fangting Chen, Ning Bao, Haiying Gu*. An ITO electrode modified with electrodeposited graphene oxide and gold nanoclusters for detecting the release of H2O2 from bupivacaine-injured neuroblastoma cells. Microchimica Acta, 2016, 183: 3167–3175
11. Weibo Li, Dongping Qian, Qiuhong Wang, Yubin Li, Ning Bao, Haiying Gu*, Chunmei Yu*. Fully-drawn origami paper analytical device for electrochemical detection of glucose, Sensors and Actuators B, 2016, 231: 230–238.
12. Weibo Li, Dongping Qian, Yubin Li, Ning Bao, Haiying Gu*, Chunmei Yu*. Fully-drawn pencil-on-paper sensors for electroanalysis of dopamine, Journal of Electroanalytical Chemistry, 2016, 769: 72–79.
13. Qiuhong Wang, Weibo Li, Ning Bao, Chunmei Yu*, Haiying Gu*. Low-potential amperometric determination of NADH using a disposable indium-tin-oxide electrode modified with carbon nanotubes. Microchimica Acta, 2016, 183: 423–430.
14. Qiuhong Wang, Weibo Li, Dongping Qian, Yubin Li, Ning Bao, Haiying Gu*, Chunmei Yu*. Paper−based analytical device for detection of extracellular hydrogen peroxide and its application to evaluate drug−induced apoptosis, Electrochimica Acta, 2016, 204: 128–135.
15. Chunmei Yu#, Li Wang#, Chun Zhu, Ning Bao, Haiying Gu*, Detection of cellular H2O2 in living cells based on horseradish peroxidase at Au nanoparticles decorated graphene oxide interface, Sensors and Actuators B: Chemical, 2015, 211: 17-24
16. Chunmei Yu, Qiuhong Wang,Weibo Li,Yubin Li,Shuxian Liu,Ning Bao,Haiying Gu*, Paper-based cell impedance sensor and its application for cytotoxic evaluation, Nanotechnology, 2015, 26: 325501
17. Chunmei Yu, Zhenkun Zhu, Qiuhong Wang, Wei Gu, Ning Bao, Haiying Gu*. Disposable indium-tin-oxide sensor modified by gold nanorod-chitosan nanocomposite for the detection of H2O2 in cancer cells. Chemical Communication, 2014, 50: 7329–7331.
18. Chunmei Yu, Zhenkun Zhu, Li Wang, Qiuhong Wang, Ning Bao, Haiying Gu*. A new disposable electrode for electrochemical study of leukemia K562 cells and anticancer drug sensitivity test. Biosensors and Bioelectronics, 2014, 53: 142–147.
19. Chunmei Yu, Li Wang, Zhenkun Zhu, Ning Bao, Haiying Gu*. Trans-membrane electron transfer in red blood cells immobilized in a chitosan film on a glassy carbon electrode. Microchimica Acta, 2014, 181:55–61.
20. Chunmei Yu, Yidan Wang, Li Wang, Zhenkun Zhu, Ning Bao, Haiying Gu*. Nanostructured biosensors built with layer–by–layer electrostatic assembly of hemoglobin and Fe3O4@Pt nanoparticles. Colloids and Surfaces B, 2013, 103:231–237.
21. Chunmei Yu, Wanyu Ji, Yidan Wang, Ning Bao, Haiying Gu*. Graphene oxide–modified electrodes for sensitive determination of diethylstilbestrol. Nanotechnology, 2013, 24: 115502.
22. Chunmei Yu, Wanyu Ji, Lili Gou, Ning Bao, Haiying Gu*. The pH-sensitiveswitchable behavior based on the layer-by-layer films of hemoglobin and Ag nanoparticles. Electrochemistry Communications, 2011, 12: 1202-1205.
23. Chunmei Yu, Lili Gou, Xiaohui Zhou, Ning Bao, Haiying Gu*. Chitosan-Fe3O4 Nanocomposite Based Electrochemical Sensors for the Determination of Bisphenol A. Electrochimica Acta, 2011, 56: 9056-9063.
24. Chunmei Yu, Xiaohui Zhou, Haiying Gu*. Immobilization, direct electrochemistry and electrocatalysis of hemoglobin on colloidal silver nanoparticles-chitosan film. Electrochimica Acta, 2010, 55: 8738-8743.
25. Chunmei Yu, Jianwei Guo, Haiying Gu*. Electrocatalytical oxidation of nitrite and its determination based on Au@Fe3O4 nanoparticles. Electroanalysis, 2010, 22: 1005-1011.
26. Chunmei Yu, Jianwei Guo, Haiying Gu*. Direct electrochemical behavior of hemoglobin at surface of Au@Fe3O4 magnetic nanoparticles. Microchimica Acta, 2009, 166: 215-220.
科研项目:
(1)国家自然科学基金委员会,应急管理项目,31741051,基于层层组装血红蛋白纳米囊氧载体的构建及其携氧机制研究,2018-01至2018-12,15万元,已结题,主持
(2)江苏省自然科学基金面上项目,BK20151267,基于微囊包裹血红蛋白阵列的人工红细胞研究,2015/07-2018/06,主持
(3)国家自然科学基金青年基金项目,31400315,植物抗病相关激素的多位点实时检测及其互作研究,2015/01-2017/12,参加
获得奖项:
于春梅(1/3),可抛型纸基电极对白血病细胞的研究及抗癌药物敏感性测定,南通市人民政府,南通市第九届自然科学优秀学术论文,一等奖,2015