刘金霞
博士 校聘副教授,江苏省“双创博士”
刘金霞,博士研究生,校聘副教授,江苏省“双创博士”。2019年6月毕业于东南大学并获得工学博士学位(导师:丁收年教授),2019年7月加入南通大学公共卫生学院。迄今为止,在Analytical Chemistry, Biosensors and Bioelectronics, Sensors and Actuators B: Chemical等国内外知名学术期刊发表SCI论文20余篇,其中以第一作者或通讯作者发表SCI论文12篇。申请国家发明专利20多项,其中授权9项。
研究方向
生物医学传感:电化学、电化学发光及光电化学生物传感器
即时检验方向:微电极的研制,微流控纸芯片的设计与开发
科研项目
1. 具有双信号放大性能的超灵敏免疫传感器构建及应用研究(22KJB330008),江苏省高等学校基础科学(自然科学)研究面上项目,2022.07-2024.06,在研,主持。
2. 新型电致化学发光纳米探针设计及其多组份恶性肿瘤生物标志物分析应用研究(JC2020099),南通市基础科学研究计划项目,2020.10-2022.09,已结题,主持。
3. 江苏省“双创博士”资助项目,2020.07-2022.07,已结题,主持。
4. 多色量子点电化学发光多组份免疫检测研究,南通大学人才引进项目(科研启动经费),2019.10-2022.09,已结题,主持。
5. 《临床检验仪器与技术》课程的教学改革探索(2020B46),南通大学教学改革科研项目,2020.09-2021.09,已结题,主持。
学术论文
1. Jinxia Liu#, Xiaodi Liu#, Huanhuan Chen, Luxia Yang, Aiting Cai, Haiwei Ji*, Qi Wang, Xiaobo Zhou, Guo Li, Mingmin Wu, Yuling Qin*, Li Wu*, Bifunctional Pdots-based novel ECL nanoprobe with qualitative and quantitative dual signal amplification characteristics for trace cytokine analysis, Anal. Chem., 2022, 94 (19): 7115-7122. (SCI一区, IF=8.008, Nature Index)
2. Jinxia Liu, Luxia Yang, Shijie Li, Ke Zhang, Xiaobo Zhou, Guo Li, Li Wu*, Yuling Qin*, Near-infrared electrochemiluminescence biosensors facilitated by thermally activated delayed fluorescence (TADF) emitters for ctDNA analysis, Biosens. Bioelectron., 2024, 251:116103(SCI一区, IF=12.6)
3. Luxia Yang#, Xijuan Gu#, Jinxia Liu*, Li Wu*, Yuling Qin*, Functionalized nanomaterials-based electrochemiluminescent biosensors and their application in cancer biomarkers detection, Talanta, 2024, 267:116103(通讯作者, SCI一区, IF=6.1)
4. Luxia Yang#, Xiaobo Zhou#, Ke Zhang, Jinxia Liu*, Lingfeng Zhao, Aiting Cai, Xinyuan Zhao, Li Wu*, Yuling Qin*, Electrochemiluminescent/electrochemical ratiometric biosensor for extremely specific and ultrasensitive detection of circulating tumor DNA, Sensor Actuat B-Chem, 2023, 382: 133490(通讯作者, SCI一区, IF=9.221)
5. Jin-Xia Liu, Xiu-Li Liang, Feihong Chen, Shou-Nian Ding*, Ultrasensitive amperometric cytosensor for drug evaluation with monitoring early cell apoptosis based on Cu2O@PtPd nanocomposite as signal amplified label, Sensor Actuat B-Chem, 2019, 300: 127046(SCI一区,IF=9.221)
6. Jin-Xia Liu and Shou-Nian Ding*, Non-enzymatic amperometric determination of cellular hydrogen peroxide using dendrimer-encapsulated Pt nanoclusters/ carbon nanotubes hybrid composites modified glassy carbon electrode, Sensor Actuat B-Chem, 2017, 251: 200-207. (SCI一区,IF=9.221)
7. Jinxia Liu, Xiaodi Liu, Luxia Yang, Aiting Cai, Xiaobo Zhou*, Chu Zhou, Guo Li, Qi Wang, Mingmin Wu, Li Wu, Haiwei Ji*, Yuling Qin*, A highly sensitive electrochemical cytosensor based on triple signal amplification strategy by using both nanozyme and DNAzyme, J. Mater. Chem. B, 2021, 10 (5): 700-706
8. Aiting. Cai, Luxia Yang, Xiaoxia Kang, Jinxia Liu*, Feng Wang*, Haiwei Ji, Qi Wang, Mingmin Wu, Guo Li, Xiaobo Zhou, Yuling Qin and Li Wu*, Target recognition and HCR amplification induced in situ electrochemical signal probe synthesis strategy for trace ctDNA analysis. Biosensors-Basel, 2022, 12 (11), 989
9. Jinxia-Liu and Shou-Nian Ding*, Multicolor electrochemiluminescence of cadmium sulfide quantum dots to detect dopamine, J. Electroanal. Chem., 2016, 781, 395-400
10. Jinxia-Liu, Ning Bao, Xiliang Luo, Shou-Nian Ding*, Nonenzymatic amperometric aptamer cytosensor for ultrasensitive detection of circulating tumor cells and dynamic evaluation of cell surface N-glycan expression, ACS Omega, 2018, 3 (8): 8595-8604
11. Jinxia-Liu and Shou-Nian Ding*, Monitoring pyrophosphate anions via cobalt (II)- modulated fluorescence of cadmium sulfide quantum dots, Anal. Methods, 2016, 8(10), 2170-2175
12. Jinxia-Liu, Mci-xia, Wu and Shou-Nian Ding*, Aggregation-induced emission enhancement of CdSe QDs by protamine and its application to sensitively and selectively detect heparin, Curr. Anal. Chem., 2019, 15 (5), 599-604
13. Xijuan Gu, Qu Tang, Xiaoxia Kang, Huoyan Ji, Xiuying Shi, Linyi Shi, Anli Pan, Yidan Zhu, Wenjun Jiang, Jing Zhang, Jinxia Liu, Mingmin Wu, Li Wu*, Yuling Qin*, A portable CRISPR-Cas12a triggered photothermal biosensor for sensitive and visual detection of Staphylococcus aureus and Listeria monocytogenes, Talanta, 2024, 271:125678 (SCI一区, IF=6.1)
14. Ke Zhang#, Xiaobo Zhou#*, Shijie Li, Lingfeng Zhao, Wenqi Hu, Aiting Cai, Yuhan Zeng, Qi Wang, Mingmin Wu, Guo Li, Jinxia Liu, Haiwei Ji, Yuling Qin*, Li Wu*, A general strategy for developing ultrasensitive “transistor-like” thermochromic fluorescent materials for multilevel information encryption, Adv. Mater., 2023, 35 (44): 2305472 (SCI一区, IF=29.4, Nature Index)
15. Guo Li, Mingmin Wu, Yongxiao Xu, Qi Wang, Jinxia Liu, Xiaobo Zhou, Haiwei Ji, Qu Tang, Xijuan Gu, Shujuan Liu, Yuling Qin*, Li Wu*, Qiang Zhao*, Recent progress in the development of singlet oxygen carriers for enhanced photodynamic therapy. Coord. Chem. Rev. 2023, 478, 214979 (SCI一区, IF=24.883)
16. Haiwei Ji#, Xiaoxia Kang#, Xiaoxiao Yang, Huanhuan Chen, lvyang Zhu, Tianzhi Mao, Yue He, Jinxia Liu, Qi Wang, Xiaobo Zhou, Guo Li, Mingmin Wu, Hui Cong*, Li Wu*, Yuling Qin*, Functionalized graphene-based electrochemical array sensors for the identification of distinct conformational states of amyloid beta in alzheimer’s disease, Biosens. Bioelectron., 2023, 222, 114927 (SCI一区,IF=12.545)
17. Xiaobo Zhou#*, Lingfeng Zhao#, Ke Zhang, Chaojie Yang, Shijie Li, Xiaoxia Kang, Guo Li, Qi Wang, Haiwei Ji, Mingmin Wu, Jinxia Liu, Yuling Qin* and Li Wu*, Ultrabright AIEdots with tunable narrow emission for multiplexed fluorescence imaging, Chem. Sci., 2023, 14, 113-120(SCI一区,IF=9.969, Nature Index)
18. Xiaobo Zhou, Yuhan Zeng, Shijie Li, Ke Zhang, Lingfeng Zhao, Guo Li, Qi Wang, Haiwei Ji, Mingmin Wu, Jinxia Liu, Yuling Qin*, Wei Feng, Fuyou Li*, Li Wu*, Polymeric engineering of AIEgens for NIR-II fluorescence imaging and detection of abdominal metastases of ovarian cancer in vivo, J. Mater. Chem. B, 2023, 11 (47), 11217-11221
19. Haiwei Ji, Haolu Hu, Qu Tang, Xiaoxia Kang, Xiaodi Liu, Lingfeng Zhao, Rongrong Jing, Mingmin Wu, Guo Li, Xiaobo Zhou, Jinxia Liu, Qi Wang, Hui Cong, Li Wu*, Yuling Qin*, Precisely controlled and deeply penetrated micro-nano hybrid multifunctional motors with enhanced antibacterial activity against refractory biofilm infections, J. Hazard. Mater. 2022, 436, 129210.(SCI一区,IF=14.224)
20. Qingqing Bai, Chaojie Yang, Majun Yang, Zhaoqing Pei, Xiaobo Zhou, Jinxia Liu, Haiwei Ji, Guo Li, Mingmin Wu, Yuling Qin, Qi Wang*, Li Wu*, pH-dominated selective imaging of lipid droplets and mitochondria via a polarity-reversible ratiometric fluorescent probe, Anal. Chem., 2022, 94 (6): 2901-2911. (SCI一区, IF=8.008, Nature Index)
21. Guo Li, Qi Wang, Jinxia Liu, Mingmin Wu, Haiwei Ji, Yuling Qin*, Xiaobo Zhou*, Li Wu*, Innovative strategies for enhanced tumor photodynamic therapy. J. Mater. Chem. B, 2021, 9, 7347-7370
22. Tang, Qu, Xiaobo Zhou, JinXia Liu, Mingmin Wu, Haiwei Ji*, Qi Wang, Guo Li, Hui Cong* and Yuling Qin*. Hydrogen generation over Ni@Pd NCs through an active H-exchange from formic acid-water system. Int. J. Hydrogen Energ. 2022, 47 (51): 21745-21752
23. Xiu-Li Liang, Jin-Xia Liu, Yong-Jun Jiao, Jin Zhu, Shou-Nian Ding*, Quantitative detection of severe fever with thrombocytopenia syndrome virus via electrochemiluminescence immunoassay, Anal. Methods, 2019, 11(32): 4197-4203