姓名 仇梁林

职称 副教授 硕士生导师

电话 051385012911

个人简介

男，江苏兴化人，医学博士，营养与食品卫生学系教师、副教授、硕士研究生导师，中国营养学会会员、江苏省毒理学会青年委员会常务委员。本科毕业于南通医学院临床医学系；硕士毕业于南通大学公共卫生学院；博士毕业于南京医科大学公共卫生学院；曾在英国Leicester University短期交流并在美国University of Maryland从事过两年的博士后研究工作。近年来主持完成多项国家、省市级科研项目，发表学术论文数十篇。

专业研究领域

营养与食品卫生学、食品毒理学、环境污染物与生殖健康

专著与论集

1. 21世纪创新系列教材 《预防医学》第四版，2021，东南大学出版社（参编）

2. 21世纪创新系列教材 《预防医学》第三版，2014，东南大学出版社（参编）

3. Preventive Medicine（预防医学）英文版，2020， 浙江大学出版社（参编）

学术论文（选填）

1 Shaokai Zheng; Ting Li; Lianglin Qiu. Identification of Potential Crucial Genes in Testicular Germ Cell Tumors: A Bioinformatical Integrated Analysis. Cancer Biomarkers. 2023. In press.

2. Shaokai Zheng; Nannan Zhao; Xiaojun Lin; Lianglin Qiu. Impacts and potential mechanisms of fine particulate matter (PM2.5) on male testosterone biosynthesis disruption. Reviews on Environmental Health. 2023. In press.

3. Shaokai Zheng ;Lianlian Jiang ; Lianglin Qiu. The effects of fine particulate matter on the blood-testis barrier and its potential mechanisms. Rev Environ Health . 2022 Nov 29. doi: 10.1515/reveh-2022-0204. Online ahead of print.

4. Huang, Jiyan; Ren, Hang; Chen, Anni; Li, Ting; Wang, Hongxia; Jiang, Lianlian; Zheng, Shaokai; Qi, Han; Ji, Binyan; Wang, Xipei; Qu, Jianhua; Zhao, Jianya; Qiu, Lianglin. Perfluorooctane sulfonate induces suppression of testosterone biosynthesis via Sertoli cell-derived exosomal/miR-9-3p downregulating StAR expression in Leydig cells. Environmental Pollution. 2022. doi:10.1016/j.envpol.2022.118960

5. Qiu, Lianglin; Chen, Minjie; Wang, Xiaoke; Chen, Sufang; Ying, Zhekang. PM2.5 Exposure of Mice during Spermatogenesis: A Role of Inhibitor κB Kinase 2 in Pro-Opiomelanocortin Neurons. Environmental Health Perspectives. 2021. doi: 10.1289/EHP8868. Epub 2021 Sep 8.

6. Chen, Minjie; Xu, Yanyi; Wang, Wanjun; Wang, Xiaoke; Qiu, Lianglin; Chen, Sufang; Kan, Haidong; Ying, Zhekang. Paternal Exposure to PM(2.5) Programs Offspring's Energy Homeostasis. Environ Sci Technol. 2021 May 4;55(9):6097-6106.

7.Lianglin Qiu, Hongxia Wang, Tianyi Dong, Jiyan Huang, Ting Li, Hang Ren, Xipei Wang, Jianhua Qu, Shoulin Wang. Perfluorooctane sulfonate (PFOS) disrupts testosterone biosynthesis via CREB/CRTC2/StAR signaling pathway in Leydig cells. Toxicology，2020, doi: 10.1016/j.tox.2020.152663.

8. Lianglin Qiu, Chao Wang, Shen Yao, Na Li, Yuhuan Hu, Yongquan Yu, Rong Xia, Jiansheng Zhu, Minghui Ji, Zhan Zhang, Shou-Lin Wang,Fenvalerate induces oxidative hepatic lesions throughan overload of intracellular calcium triggered by theERK/IKK/NF-kB pathway. FASEB J,2019 33(2):2782-2795.

9. Chen, Sufang; Chen, Minjie; Wei, Wei; Qiu, Lianglin; Zhang, Li; Cao, Qi; Ying, Zhekang. Glucose Homeostasis following Diesel Exhaust Particulate Matter Exposure in a Lung Epithelial Cell-Specific IKK2-Deficient Mouse Model. Environmental Health Perspectives. 2019. May;127(5):57009.

10. Qiu L, Chen M, Wang X, Qin X, Chen S, Qian Y, Liu Z, Cao Q, Ying Z.Exposure to Concentrated Ambient PM2.5 Compromises Spermatogenesis in a Mouse Model: Role of Suppression of Hypothalamus-Pituitary-Gonads Axis. Toxicol Sci. 2018;162(1):318-326

11. Chen, Minjie; Qin, Xiaobo; Qiu, Lianglin; Chen, Sufang; Zhou, Huifen; Xu, Yanyi; Hu, Ziying; Zhang, Yuhao; Cao, Qi; Ying, Zhekang. Concentrated Ambient PM2.5-Induced Inflammation and Endothelial Dysfunction in a Murine Model of Neural IKK2 Deficiency. Environ Health Perspect. 2018 Feb 5;126(2):027003.

12. Chen, Minjie; Liang, Shuai; Qin, Xiaobo; Zhang, Li; Qiu, Lianglin; Chen, Sufang; Hu, Ziying; Xu, Yanyi; Wang, Wanjun; Zhang, Yuhao; Cao, Qi; Ying, Zhekang. Prenatal exposure to diesel exhaust PM(2.5) causes offspring β cell dysfunction in adulthood. Am J Physiol Endocrinol Metab. 2018 Jul 1;315(1):E72-E80.

13. Chen, Sufang; Wei, Wei; Chen, Minjie; Qin, Xiaobo; Qiu, Lianglin; Zhang, Li; Zhang, Yuhao; Cao, Qi; Ying, Zhekang. TNF Signaling Impacts Glucagon-Like Peptide-1 Expression and Secretion. J Mol Endocrinol. 2018 Oct 15;61(4):153-161

14. Lianglin Qiu，Yingyun Qian，Zhenzhen Liu，Chao Wang，Jianhua Qu，Xiaoke Wang，Shoulin Wang，Perfluorooctane sulfonate (PFOS) disrupts blood-testis barrier by down-regulating junction proteins via p38 MAPK/ATF2/MMP9 signaling pathway，Toxicology，2016, 373：1-12.

15. Qiu L, Zhang X, Zhang X, Zhang Y, Gu J, Chen M, Zhang Z, Wang X, Wang SL. Sertoli cell is a potential target for perfluorooctane sulfonate-induced reproductive dysfunction in male mice. 2013. Toxicol Sci 135(1): 229-40.

16. Qiu LL, Wang X, Zhang XH, Zhang Z, Gu J, Liu L, Wang Y, Wang X, Wang SL. Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A. 2013. Toxicol Lett 219(2):116-24

17.Lu HY, Qiu LL, Yang XJ, Zhang XM, Zhang Z, Wang SL. Optimization of heme precursors for the expression of human cytochrome P450 2A13 and its co-expression with oxidoreductase in baculovirus/sf9 system. 2013. J Biochem 153(6):555-63

主要科研项目

1.主持完成国家自然科学基金青年项目1项（81302452）

2.主持在研江苏省科技厅自然科学基础研究面上项目1项(BK20221374)

3.主持完成江苏省教育厅高等学校自然科学研究项目1项（12kJB330004）

4.主持完成江苏省教育厅高等学校自然科学研究项目1项（18kJB330004）

5.主持完成南通市科技局基础研究项目一项（JC2019021）

6.主持完成南通大学博士科研人员启动基金项目一项。

讲授课程

营养与食品卫生学、临床营养学、行为生活方式与健康、预防医学进展、健康教育

指导研究生情况

目前已指导学术型和专业型硕士研究生11名